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PORE FORMING CYTOTOXIC PROTEINS
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DeCS
Descriptor
English
:
Pore Forming Cytotoxic Proteins
Descriptor
Spanish
:
Proteínas Citotóxicas Formadoras de Poros
Descriptor
Portuguese
:
Proteínas Citotóxicas Formadoras de Poros
Tree Number:
D12.776.543.695
Definition
English
:
Proteins
secreted from an organism which form membrane-spanning pores in target
cells
to destroy them. This is in contrast to
PORINS
and
MEMBRANE TRANSPORT PROTEINS
that function within the synthesizing organism and COMPLEMENT immune
proteins
. These
pore forming cytotoxic proteins
are a form of primitive cellular defense which are also found in human
LYMPHOCYTES.
See Related
English
:
Porins
History Note
English
:
2007
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52332
Unique Identifier:
D052899
Occurrence in VHL
:
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